xCELLigence Resources - ACEA Biosciences Inc.

Optimization of Chimeric Antigen Receptor (CAR) T Cell Design Guided by Sensitive Assessment of B Cell KillingAdoptive cellular therapy using chimeric antigen receptor (CAR) T cells has produced significant responses in patients with CD19+ hematological malignancies. Most clinical trials...Read More

CYTO 2017: Combining Real-Time Cell Analysis With Flow Cytometry to Characterize BiTE/T Cell-Mediated Cytolysis and Neutrophil Extracellular Traps

ASCB 2016 Tech Seminar: Label-Free Real-Time Monitoring of Immune Cell-Mediated Killing Using Cellular Impedance

Utilization of a Label-Free Real-Time Cell Analysis Technology for Cancer Immunotherapy Applications

Identifying a Novel Diagnostic and Therapeutic Target for Metastatic Breast Cancer

Evaluating Drug-Induced Proarrhythmic Risk Using the CardioECR System

Bispecific Antibody Constructs Mediate Immunotherapeutic Retargeting of Effector Cells Towards HBV Infected Target Cells

Dr. Felix Bohne
Institute of Virology, German Research Center for Environmental Health, Helmholtz Zentrum München

Chronic viral hepatitis is a major public health threat. Current strategies for eradicating the virus and treating virus-induced liver disease and hepatocellular carcinoma are very limited. Novel therapeutic strategies are in urgent need. Immunotherapeutic retargeting of effector cells is a promising approach to… Read More

Download poster

Unraveling Kinase Inhibitor Cardiotoxicity with Cardiomyocyte Impedance Assays

Dr. Sarah K. Lamore
AstraZeneca Pharmaceuticals, Waltham, MA

Cardiovascular (CV) toxicity is a leading cause of drug failure. Though implementing earlier testing has successfully reduced hERG-related arrhythmias, additional assays capable of identifying other functional CV effects remain elusive. There is a pressing need to…Read More

Download slide deck

Targeting the Reattachment of Circulating Breast Tumor Stem Cells to Reduce Metastasis

Dr. Stuart Martin
University of Maryland School of Medicine, Baltimore, MD

Breast tumor stem cells that are circulating in the bloodstream can invade distant tissues and lie dormant for long periods of time. Reemergence of these disseminated stem cells as metastatic tumors is a primary cause of patient death. In this webinar… Read More

Download slide deck

Advances in Toxicity Bioassays – Unleashing the Power of Real-Time Cell Analysis for Health Risk Assessment

Dr. Stephan Gabos
University of Alberta, Edmonton, AB (Canada)

Modern public health protection requires ongoing surveillance of environmental media (water, air, food and soil) for potentially harmful chemicals. There is currently an unmet need for in vitro toxicity assays with higher sensitivity, lower interference, and better… Read More

Download slide deck

A Novel in vitro Approach to Study Biocompatibility and Wound Healing

Dr. Sandra N. Garcia
Kinetic Concepts Inc., San Antonio, TX

Negative Pressure Wound Therapy (NPWT), where a vacuum is applied to an acute or chronic wound, has proven extremely effective for promoting would healing. The success of NPWT lies in its ability to draw the edges of a wound together, to promote granulation,…Read More

Using Impedance-Based Approaches for Measuring Antigen-Specific Cytotoxic T cell Activity

Dr. Keith L. Knutson
Mayo Clinic, Jacksonville, FL
The Vaccine & Gene Therapy Institute of Florida, Port Saint Lucie, FL

Immunotherapy, where the immune system is harnessed to treat and/or prevent disease, holds great promise in the fight against cancer. One noteworthy facet of cancer immunotherapy is the development of cancer-specific vaccines. In this webinar Dr. Keith L…Read More

Download slide deck

Identifying Novel Combination Therapeutic Targets for Pancreatic Cancer

Dr. Melissa L. Fishel
Indiana University School of Medicine, Indianapolis, IN

Pancreatic cancer is presently a largely incurable disease. Increasing evidence suggests that effective treatment strategies will need to simultaneously target multiple molecular mediators of critical functions in pancreatic ductal adenocarcinoma cells (PDAC)…Read More

Download slide deck

Cardiac Toxicity Assessment Using Stem Cell-Derived Cardiomyocytes

Dr. Matthew F. Peters
AstraZeneca Pharmaceuticals, Boston, MA

Cardiac toxicity is a major hurdle in drug development. In this webinar Dr. Matthew F. Peters of AstraZeneca Pharmaceuticals (Boston, MA) discusses the utility of combining ACEA Bioscience’s xCELLigence® Cardio system with stem cell-derived cardiomyocytes...Read More

Tutorials

Cell Adhesion Assay with iCELLigence – a Hands on Video

Cell Migration Assay with xCELLigence DP – a Hands-on Video

For French audio, please click here.

Cytotoxicity Assay with xCELLigence SP – a Hands-on Video

J.O.V.E. Video Articles

Determining Optimal Cytotoxic Activity of Human Her2neu Specific CD8 T-Cells by Comparing the Cr51 Release Assay to the xCELLigence System (Keith Knutson on JOVE)

Assessment of Ovarian Cancer Spheroid Attachment and Invasion of Mesothelial Cells in Real Time (Maree Bilandzic on JOVE)

A Real-Time Electrical Impedance Based Technique to Measure Invasion of an Endothelial Cell Monolayer by Cancer Cells (Aykut Uren on JOVE)

Testimonials

Jason Maynes Testimonial

Blake Anson Testimonial

Cell Lines

Each of the >360 cell lines listed here has been successfully analyzed using an xCELLigence RTCA system.

For more information, or to contact Technical Support, please call or email us :

Phone: 858-724-0928 | Toll Free: 1-866-308-2232 | Email: techsupport@aceabio.com

	Catalog Number
Products	Complete Kit	Tethering Kit	Sample Kit
B Cell Killing (anti-CD40) Assay	8100004	8100005	8100006
B Cell Killing (anti-CD19) Assay	8100010	8100011	8100012
Leukemic Cell Killing (anti-CD29) Assay	8100007	8100008	8100009