Register for the 4th Annual Cardio Symposium, September 16-17, immediately prior to the 2016 SPS Meeting in Vancouver, Canada.
Cardiotoxicity and cardiac liability continues to be a major hurdle in drug development. Within the pharmaceutical industry, academic institutions, and regulatory agencies there are ongoing efforts to develop higher throughput and more predictive assays that can be used earlier in the drug discovery/development pipeline to minimize both cost and risk.
ACEA Biosciences’ annual Cardio Symposium is a forum to promote scientific exchange and collaboration amongst scientists working at the forefront of cardiac safety assessment and cardiovascular disease model research. Experts from both industry and academia will share their findings on combining human induced pluripotent stem cell-derived (hiPSC) cardiomyocytes, cellular impedance, MEA and other technologies for cardiac safety assessment and cardiovascular disease studies.
|Friday, September 16, 2016|
|4:30 PM – 6:00 PM||Registration|
|6:00 PM – 9:00 PM||Welcome Reception and Poster Session|
|Even # Poster Presentation (6:00 PM – 7:00 PM)|
|Odd # Poster Presentation (7:00 PM – 8:00 PM)|
|Saturday, September 17, 2016|
|7:30 AM – 8:20 AM||Breakfast & Registration|
|8:20 AM – 8:50 AM||Welcome and introduction||Yama Abassi, Ph.D. (ACEA
|Session I: Cardiovascular Disease Models & Therapy|
|8:55 AM – 9:20 AM||Measuring Clinical Cardiac Effect and Toxicity||Jason Maynes, M.D., Ph.D. (The Hospital for Sick Children, CANADA)|
|9:25 AM – 9:50 AM||Human iPSC cardiomyocytes recapitulate bradycardia observed in patients treated with sphingosine-1-phosphate receptor agonists||Hong Shi, M.D. (Bristol-Myers
|9:55 AM – 10:20 AM||Human Induced Pluripotent Stem Cells Capture Clinical Heterogeneity In Hearts of Cardiomyopathy Patients and Provide A Platform To Uncover Therapeutics||Farah Sheikh, Ph.D., FCVS, FAHA (University of California, San Diego, USA)|
|10:25 AM – 10:55 AM||Morning Break Session|
|Session II: Cardiac Safety Discovery|
|10:55 AM – 11:20AM||Towards a Better Understanding of the Impedance Signal as an Indirect Measurement of Contractility in iCells/hIPSC-derived Cardiomyocytes||Maria Roman, Ph.D. (Merck
Research Labs, USA)
|11:25 AM – 11:50 AM||Identify Biomarkers to Predict Tyrosine Kinase Inhibitors (TKIs) -Induced Cardiotoxicity Using iPSC- Derived Cardiomyocytes||Xi Yang, Ph.D. (Division of
Systems Biology/ National Center for Toxicological Research at FDA, USA)
|11:55 AM – 12:20 PM||Clinically relevant electrophysiological properties of human iPS cell-derived cardiomyocytes for the assessment of drug-induced Torsade de pointes risk||Kohei Sawada, Ph.D. (Eisai,
|12:25 PM – 1:30 PM||Lunch & Networking (Group Photo @ 12:30 PM)|
|Session III: Cardiac Safety Assessment|
|1:30 PM –1:55 PM||Human Stem Cell Derived Cardiomyocytes in Cardiac Safety Assessment||Ksenia Blinova, Ph.D. (Food and Drug Administration, USA)|
|2:00 PM –2:25 PM||Maturation of Human iPSC-cardiomyocytes in Long-term Culture for Cardiotoxicity Testing||Liang Guo, M.D., M.Sc. (FNLCR/NCI, USA)|
|2:30 PM –2:55 PM||Evaluation of batch variations in induced pluripotent stem cell derived- human cardiomyocytes from two major suppliers||Li Pang, M.D. (National Center for Toxicological Research at FDA, USA)|
|3:00 PM – 3:10 PM||Developing high quality reagents, assays and platforms for predictive cardiac safety screening: validating stem cell-derived iPS cardiomyocytes on patch clamp and phenotypic platforms.||Marc Rogers, Ph.D. (Metrion Biosciences, UK)|
|3:15 PM – 3:30 PM||Afternoon Break Session|
|3:30 PM – 3:55 PM||Activity of Japan iPS Cardiac Safety Assessment (JiCSA) toward the new strategy of the Safety Pharmacology||Yuko Sekino, Ph.D. (National Institute of Health Sciences, JAPAN)|
|4:00 PM – 5:00 PM||Panel Discussion- Cardio Safety Assessment using iPSC Cardiomyocyte and Future Regulatory Decision|
|5:00 PM||Meeting Concludes|
Hyatt Regency Vancouver
655 Burrard St, Vancouver, BC V6C 2R7, Canada
Group rate: starts from 269 CAD. Book by September 1st, 2016 for group rates.
In order to book your guest room at the Hyatt Regency Vancouver, please click here for online reservations.