RT-CES® System is a novel cell-based assay system to monitor cellular events by measuring the electronic impedance of sensor electrodes integrated on the bottom of microtiter E-Plates. Based on measured impedance a dimensionless parameter, Cell Index, is derived and reported to provide quantitative information about the biological status of the cells, including cell number, viability, morphology, and cytoskeletal dynamics. A wide range of cell-based assays can be performed on the RT-CES® system.